教育及工作经历：

2022.08至今，yh1122银河国际，yh1122银河国际，助理教授

2020.07~2022.09，yh1122银河国际，生物学，博士后

2014.09~2020.06，西北农林科技大学，水生生物学，理学博士

2010.09~2014.06，西北农林科技大学，水产养殖学，农学学士

主持科研项目：

（1）国家自然基金青年科学基金项目（42106133）：基于ABPP策略的天然分子京尼平抗对虾WSSV靶标的确证及机制研究，2022.01 - 2024.12，主持。

（2）中国博士后科学基金面上项目（2021M693796）：抗对虾WSSV天然分子京尼平苷酸的作用靶标鉴定，2021.07-2022.08，主持。

（3）广西自然科学基金青年基金项目（2021GXNSFBA075008）：靶向毒力因子抗罗非鱼无乳链球菌纳米抗体研究，2021.04-2024.03，主持。

（4）广西科技基地和人才专项（桂科AD22080029）：基于肠道菌群研究中草药抗对虾WSSV作用机制，2022.07-2025.06，在研，主持。

（5）yh1122银河国际高层次人才项目，2022-2025年，主持。

发表论文：

目前发表SCI论文25篇。以第一作者发表研究性SCI论文9篇，包含中科院1区TOP论文6篇。

（1）     Ai-Guo Huang, Wei-Hao He, Lin-Jun Su, Fa-Li Zhang, Ying-Hui Wang*, 2022. Identification of a camelid-derived nanobody as a potential therapeutic agent against Streptococcus agalactiae infection. Aquaculture. 561, 738725.

（2）     Huang Ai-Guo, He Wei-Hao, Zhang Fa-Li, Wei Chao-Shuai, Wang Ying-Hui*, 2022. Natural component geniposide enhances survival rate of crayfish Procambarus clarkii infected with white spot syndrome virus. Fish & Shellfish Immunology. 126, 96-103.

（3）     Huang Ai-Guo, Chen Cheng, Liu Tian-Qiang, Wang Gao-Xue*. 2022. scFv antibody-mediated targeted drug delivery system improves the antiviral activity of geniposidic acid against WSSV. Aquaculture. 560, 738496.

（4）     Huang Ai-Guo, Su Lin-Jun, He Wei-Hao, Zhang Fa-Li, Wei Chao-Shuai, Wang Yin-Hui*, 2022. Natural component plumbagin as a potential antibacterial agent against Streptococcus agalactiae infection. Journal of Fish Diseases. 00, 1-9.

（5）     Huang Ai-Guo, Tan Xiao-Ping, Cui Hai-Bo, Qi Xiao-Zhou, Zhu Bin*, Wang Gao-Xue*, 2020. Antiviral activity of geniposidic acid against white spot syndrome virus replication in red swamp crayfish Procambarus clarkii. Aquaculture. 528, 735533.

（6）     Huang Ai-Guo, Tan Xiao-Ping, Qu Shen-Ye, Wang Gao-Xue*, Zhu Bin*, 2019. Evaluation on the antiviral activity of genipin against white spot syndrome virus in crayfish. Fish & Shellfish Immunology. 93, 380-386.

（7）     Huang Ai-Guo, Tu Xiao, Qi Xiao-Zhou, Ling Fei, Zhu Bin*, Wang Gao-Xue*, 2019. Gardenia jasminoides Ellis inhibit white spot syndrome virus replication in red swamp crayfish Procambarus clarkii. Aquaculture. 504, 239-247.

（8）     Huang Ai-Guo, Tu Xiao, Liu Lei, Wang Gao-Xue*, Ling Fei*, 2016. The oxidative stress response of myclobutanil and cyproconazole on Tetrahymena thermophila. Environmental Toxicology and Pharmacology. 41, 211-218.

（9）     Huang Ai-Guo, Yi Yang-Lei, Ling Fei, Lu Lin, Zhang Qi-Zhong, Wang Gao-Xue*, 2013. Screening of plant extracts for anthelmintic activity against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus). Parasitology Research. 112, 4065-4072.

（10） Zhu Song, Huang Ai-Guo, Luo Fei, Li Jian, Li Jing, Zhu Long, Zhao Liang, Zhu Bin, Ling Fei, Wang Gao-Xue*, 2019. Application of Virus Targeting Nanocarrier Drug Delivery System in Virus-Induced Central Nervous System Disease Treatment. ACS applied materials & interfaces. 11, 19006-19016.

（11） Tu Xiao, Huang Aiguo, Hu Yang, Ling Fei, Wang Gaoxue*, 2018. Arctigenin: An emerging candidate against infections of Gyrodactylus. Aquaculture. 495, 983-991.

（12） Tu Xiao, Qi Xiaozhou, Huang Aiguo, Ling Fei, Wang Gaoxue*, 2019. Cytokine gene expression profiles in goldfilsh (Carassius auratus) during Gyrodactylus kobayashii infection. Fish & Shellfish Immunology. 86, 116-124.

（13） Zhu Song, Li Jian, Huang Ai-Guo, Huang Ji-Qiu, Huang Yong-Quan, Wang Gao-Xue*, 2019. Anti-betanodavirus activity of isoprinosine and improved efficacy using carbon nanotubes based drug delivery system. Aquaculture. 512.

（14） Zhu Song, Zhu Bin, Huang Aiguo, Hu Yang, Wang Gaoxue*, Ling Fei*, 2016. Toxicological effects of multi-walled carbon nanotubes on Saccharomyces cerevisiae: The uptake kinetics and mechanisms and the toxic responses. Journal of Hazardous Materials. 318, 650-662.

（15） Ling Fei, Tu Xiao, Huang Aiguo, Wang Gaoxue*, 2016. Morphometric and molecular characterization of Dactylogyrus vastator and D-intermedius in goldfish (Carassius auratus). Parasitology Research. 115, 1755-1765.

（16） Song Kaige, Ling Fei, Huang Aiguo, Dong Wenjing, Liu Guanglu, Jiang Chao, Zhang Qizhong, Wang Gaoxue*, 2015. In vitro and in vivo assessment of the effect of antiprotozoal compounds isolated from Psoralea corylifolia against Ichthyophthirius multifiliis in fish. International Journal for Parasitology-Drugs and Drug Resistance. 5, 58-64.

（17） Tu Xiao, Ling Fei, Huang Aiguo, Wang Gaoxue*, 2015. An infection of Gyrodactylus kobayashii Hukuda, 1940 (Monogenea) associated with the mortality of goldfish (Carassius auratus) from central China. Parasitology Research. 114, 737-745.

（18） Tu Xiao, Ling Fei, Huang Aiguo, Wang Gaoxue*, 2015. The first report of Dactylogyrus formosus Kulwiec, 1927 (Monogenea: Dactylogyridae) from goldfish (Carassius auratus) in central China. Parasitology Research. 114, 2689-2696.

（19） Tu Xiao, Ling Fei, Huang Aiguo, Zhang Qizhong, Wang Gaoxue*, 2013. Anthelmintic efficacy of Santalum album (Santalaceae) against monogenean infections in goldfish. Parasitology Research. 112, 2839-2845.

（20） Tu Xiao, Tan Xiaoping, Qi Xiaozhou, Huang Aiguo, Ling Fei*, Wang Gaoxue*, 2020. Proteome interrogation using gold nanoprobes to identify targets of arctigenin in fish parasites. Journal of Nanobiotechnology. 18, 32.

（21） Qi Xiao-Zhou, Tu Xiao, Zha Ji-Wei, Huang Ai-Guo, Wang Gao-Xue*, Ling Fei*, 2019. Immunosuppression-induced alterations in fish gut microbiota may increase the susceptibility to pathogens. Fish & Shellfish Immunology. 88, 540-545.

（22） Chen Xiaohui, Hao Kai, Yu Xiaobo, Huang Aiguo, Zhu Bin, Wang Gao-xue*, Ling Fei*, 2018. Magnolol protects Ctenopharyngodon idella kidney cells from apoptosis induced by grass carp reovirus. Fish & Shellfish Immunology. 74, 426-435.

（23） Ling Fei, Lu Cheng, Tu Xiao, Yi Yanglei, Huang Aiguo, Zhang Qizhong, Wang Gaoxue*, 2013. Antiprotozoal screening of traditional medicinal plants: evaluation of crude extract of Psoralea corylifolia against Ichthyophthirius multifiliis in goldfish. Parasitology Research. 112, 2331-2340.

（24） Zhang Chen, Li Lin-Han, Wang Jin, Zhao Zhao, Li Jian, Tu Xiao, Huang Ai-Guo, Wang Gao-Xue*, Zhu Bin*, 2018. Enhanced protective immunity against spring viremia of carp virus infection can be induced by recombinant subunit vaccine conjugated to single-walled carbon nanotubes. Vaccine. 36, 6334-6344.

（25） He Maosheng, Liu Gaoyang, Liu Yihang, Yang Kechen, Qi Xiaozhou, Huang Aiguo, Liu Tianqiang, Wang Gaoxue*, Wang Erlong*, 2020. Effects of geniposide as immunostimulant on the innate immune response and disease resistance in crucian carp. Aquaculture. 529, 735713.